Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83812 | 0.78 | CES2 (0.50) | CES2CES1FAAHAKR1B1 | |
| SCHEMBL1723738 | 0.76 | CES2 (0.58) | CES2TSHRALDH1A1CES1FAAH | |
| SCHEMBL7953024 | 0.76 | CES2 (0.48) | CES2TSHRCES1FAAHAKR1B1 | |
| SCHEMBL1908016 | 0.76 | FAAH (0.55) | CES2TSHRCES1FAAH | |
| SCHEMBL11789802 | 0.76 | FAAH (0.55) | CES2TSHRCES1FAAH | |
| SCHEMBL11452832 | 0.76 | CES2 (0.48) | CES2TSHRCES1FAAHAKR1B1 | |
| SCHEMBL16924621 | 0.76 | CES2 (0.59) | CES2TSHRCES1FAAHAKR1B1 | |
| SCHEMBL7028977 | 0.74 | CES2 (0.61) | CES2TSHRALDH1A1CES1 | |
| SCHEMBL5423233 | 0.74 | CES2 (0.56) | CES2TSHRALDH1A1CES1FAAH | |
| SCHEMBL4661747 | 0.73 | CES2 (0.50) | CES2TSHRCES1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084725-C | Preparation of alpha-chloroalkyl aryl ketones | BASF AG (DE) | 2002-05-15 | — | — | CN | claimed |
| EP-0735016-B1 | Process for the preparation of alpha-chloroalkylarylketones | BASF AG (DE) | 1999-06-30 | — | — | EP | claimed |
| US-5710341-A | CHLORINATION OF ALKYL ARYL KETONES WITH SULFURYL CHLORIDE IN PRESENCE OF ALIPHATIC ALCOHOL | BASF AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | claimed |
| CN-1142483-A | Preparation of alpha-chloroalkyl aryl ketones | BASF AG (DE) | 1997-02-12 | — | — | CN | claimed |
| EP-0152004-B1 | PROCESS FOR PREPARING ALPHA-ARYL-ALKANOIC ACIDS | ZAMBON S.p.A. (IT) | 1988-05-25 | — | — | EP | claimed |
| US-4620031-A | Process for preparing alpha-aryl-alkanoic acids | ZAMBON S.P.A. (IT) | 1986-10-28 | — | — | US | claimed |
| US-4325985-A | Thread lock | THE OAKLAND CORPORATION (US) | 1982-04-20 | — | — | US | claimed |
| JP-8277240-A | — | — | None | — | — | JP | disclosed |
| US-20080255364-A1 | Method For The Production A-Chloroalkylpyridyl Ketones And/Or The Hydrochlorides Thereof | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-16 | — | — | US | disclosed |
| WO-1999064055-A9 | MULTIVALENT AGONISTS, PARTIAL AGONISTS, INVERSE AGONISTS AND ANTAGONISTS OF THE 5HT4 RECEPTORS | ADVANCED MEDICINE INC (US) | 2002-08-29 | — | — | WO | disclosed |
| CN-1084725-C | Preparation of alpha-chloroalkyl aryl ketones | BASF AG (DE) | 2002-05-15 | — | — | CN | disclosed |
| CN-1084725-C | Preparation of alpha-chloroalkyl aryl ketones | BASF AG (DE) | 2002-05-15 | — | — | CN | disclosed |
| CN-1084725-C | Preparation of alpha-chloroalkyl aryl ketones | BASF AG (DE) | 2002-05-15 | — | — | CN | disclosed |
| US-5710341-A | CHLORINATION OF ALKYL ARYL KETONES WITH SULFURYL CHLORIDE IN PRESENCE OF ALIPHATIC ALCOHOL | BASF AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| CN-1142483-A | Preparation of alpha-chloroalkyl aryl ketones | BASF AG (DE) | 1997-02-12 | — | — | CN | disclosed |
| CN-1142483-A | Preparation of alpha-chloroalkyl aryl ketones | BASF AG (DE) | 1997-02-12 | — | — | CN | disclosed |
| CN-1142483-A | Preparation of alpha-chloroalkyl aryl ketones | BASF AG (DE) | 1997-02-12 | — | — | CN | disclosed |
| JP-H08277240-A | PREPARATION OF ALPHA-CHLOROALKYL ARYL KETONE | BASF AG | 1996-10-22 | — | — | JP | disclosed |
| EP-0735016-A1 | Process for the preparation of alpha-chloroalkylarylketones | BASF Aktiengesellschaft (DE) | 1996-10-02 | — | — | EP | disclosed |
| US-4325985-A | Thread lock | THE OAKLAND CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255364-A1 | Method For The Production A-Chloroalkylpyridyl Ketones And/Or The Hydrochlorides Thereof | CBS, PCCA, ALK | CES2 603/4885TSHR 1649/4885ALDH1A1 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.