Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1069430 | 0.88 | ALDH1A1 (0.43) | PDE4BMAPTPDE4APDE4CPDE4D | |
| SCHEMBL1069867 | 0.80 | ALDH1A1 (0.47) | TSHRATMCYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL4853131 | 0.77 | ABL1 (0.36) | MAPTCYP3A4CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL455425 | 0.75 | MAPT (0.34) | PDE4BMAPTPDE4APDE4CPDE4D | |
| SCHEMBL1066310 | 0.75 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL28926431 | 0.74 | ERN1 (0.47) | MAPTCYP1A1CYP1A2CYP1B1ABCB1 | |
| SCHEMBL261996 | 0.71 | NQO2 (0.31) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1065307 | 0.71 | CYP1A2 (0.39) | MEN1KMT2ACYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL744349 | 0.70 | ALDH1A1 (0.43) | CYP3A4CYP1A1CYP1A2CYP2A6CYP1B1 | |
| SCHEMBL4854196 | 0.70 | ABL1 (0.33) | CYP3A4CYP1A1CYP1A2CYP2E1CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318962-A1 | Fungicides Based on Nitrogen-Containing Heterocycles | SYNGENTA CROP PROTECTION, INC. (US) | 2008-12-25 | — | — | US | disclosed |
| EP-1771423-A1 | FUNGICIDES BASED ON NITROGEN-CONTAINING HETEROCYCLES | Syngeta Participations AG (CH) | 2007-04-11 | — | — | EP | disclosed |
| WO-2005123698-A1 | FUNGICIDES BASED ON NITROGEN-CONTAINING HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318962-A1 | Fungicides Based on Nitrogen-Containing Heterocycles | DDT, CYP4X1, CBR1 | PDE4B 1891/4885MAPT 4342/4885PDE4A 2325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.