SCHEMBL4929290

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20764015	0.86	ESRRG (0.67)	SMN1; SMN2APLNRTP53MAPTGAA
	SCHEMBL5224433	0.81	HDAC2 (0.61)	SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
	SCHEMBL4928257	0.81	ESR1 (0.74)	SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
	SCHEMBL5222427	0.80	HDAC1 (0.53)	SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
	SCHEMBL4927962	0.78	MEN1 (0.58)	SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
	SCHEMBL4931342	0.78	NPC1 (0.80)	SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
	SCHEMBL4929228	0.78	SMN1; SMN2 (0.82)	SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
	SCHEMBL8714717	0.77	GAA (0.73)	SMN1; SMN2APLNRTP53MAPTGAA
	SCHEMBL20189993	0.77	SMN1; SMN2 (0.72)	SMN1; SMN2APLNRMAPTGAAKDM4E
	SCHEMBL5238765	0.74	HDAC3 (0.66)	SMN1; SMN2HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.