Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 2/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717898 | 0.96 | MRGPRX4 (0.35) | MRGPRX4EGLN1PDE4APDE4BPDE4C | |
| SCHEMBL4934191 | 0.91 | EGLN1 (0.36) | MRGPRX4EGLN1PDE4APDE4BPDE4C | |
| SCHEMBL5718269 | 0.90 | THRA (0.40) | MRGPRX4EGLN1 | |
| SCHEMBL5717902 | 0.88 | MRGPRX4 (0.33) | MRGPRX4HSD17B10CXCR3TAOK1TAOK3 | |
| SCHEMBL4926882 | 0.88 | PDE4A (0.36) | MRGPRX4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4931877 | 0.86 | PDE4A (0.35) | MRGPRX4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4931806 | 0.86 | F2 (0.39) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL4929549 | 0.85 | MRGPRX4 (0.40) | MRGPRX4EGLN1HSD17B10ITGB3ITGA2B | |
| SCHEMBL4930880 | 0.84 | MRGPRX4 (0.41) | MRGPRX4EGLN1HSD17B10ITGB3ITGA2B | |
| SCHEMBL4932680 | 0.84 | MRGPRX4 (0.42) | MRGPRX4TAOK1TAOK3PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | MRGPRX4 119/4885EGLN1 2616/4885PDE4A 897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.