Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718269 | 0.91 | THRA (0.40) | EGLN1MEN1KMT2ATHRATHRB | |
| SCHEMBL4929677 | 0.91 | MRGPRX4 (0.38) | EGLN1MRGPRX4PDE4APDE4BPDE4C | |
| SCHEMBL5717898 | 0.87 | MRGPRX4 (0.35) | EGLN1THRATHRBMRGPRX4PDE4A | |
| SCHEMBL4535685 | 0.87 | THRA (0.38) | MEN1KMT2ASMN1; SMN2THRATHRB | |
| SCHEMBL4360211 | 0.86 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2THRATHRB | |
| SCHEMBL4931128 | 0.86 | MEN1 (0.37) | MEN1KMT2ASMN1; SMN2THRATHRB | |
| SCHEMBL4922892 | 0.85 | THRB (0.50) | THRATHRBDHODHMRGPRX4PTPN1 | |
| SCHEMBL4933712 | 0.85 | EGLN1 (0.36) | EGLN1MEN1KMT2ASMN1; SMN2THRA | |
| SCHEMBL4926820 | 0.85 | EGLN1 (0.38) | EGLN1MEN1KMT2ASMN1; SMN2THRA | |
| SCHEMBL4934946 | 0.84 | SMN1; SMN2 (0.41) | EGLN1MEN1KMT2ASMN1; SMN2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | EGLN1 2616/4885MEN1 773/4885KMT2A 1742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.