Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831752 | 0.83 | ALOX15 (0.57) | LMNATBXAS1MAPT | |
| SCHEMBL6642195 | 0.82 | L3MBTL1 (0.69) | L3MBTL1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL7835421 | 0.80 | HDAC1 (0.49) | LMNA | |
| SCHEMBL9213501 | 0.75 | KDM4E (0.50) | ALDH1A1LMNACYP2C9MAPTTP53 | |
| SCHEMBL4929694 | 0.74 | HDAC6 (0.53) | L3MBTL1ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL6643638 | 0.74 | CYP4F2 (0.48) | L3MBTL1ALDH1A1CYP4F2CYP4A11LMNA | |
| SCHEMBL15920638 | 0.74 | POLB (0.59) | ALDH1A1LMNAMAPTTP53KDM4E | |
| SCHEMBL9216318 | 0.74 | CYP2C9 (0.43) | ALDH1A1LMNACYP2C9TOP2AMAPT | |
| SCHEMBL17921405 | 0.72 | SUCNR1 (0.48) | ALDH1A1CYP4F2CYP4A11LMNATBXAS1 | |
| SCHEMBL9216519 | 0.72 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1LMNACYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5804601-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, BACTERIAL OR VIRAL MENINGITIS, DOWN'S SYNDROME AND PARKINSON'S DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0737671-A2 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-10-16 | — | — | EP | disclosed |