Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886870 | 0.91 | RPS6KB1 (0.46) | CSNK2A2CSNK2A1MAOAMAOBRPS6KB1 | |
| SCHEMBL1880290 | 0.85 | KDM4E (0.51) | CSNK2A2CSNK2A1RPS6KB1AKT1KDM4E | |
| SCHEMBL4966742 | 0.74 | TAAR1 (0.46) | CSNK2A2CSNK2A1RPS6KB1AKT1KDM4E | |
| SCHEMBL12638980 | 0.72 | KDM4E (0.53) | RPS6KB1AKT1KDM4EMEN1KMT2A | |
| SCHEMBL25175693 | 0.72 | KDR (0.49) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12638986 | 0.70 | MEN1 (0.45) | CSNK2A2CSNK2A1RPS6KB1AKT1KDM4E | |
| SCHEMBL12942164 | 0.69 | MEN1 (0.47) | KDM4EMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL12639001 | 0.69 | KDM4E (0.56) | KDM4EMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL870804 | 0.69 | KDM4E (0.55) | CSNK2A2CSNK2A1KDM4EMEN1KMT2A | |
| SCHEMBL1633004 | 0.69 | ALDH1A1 (0.45) | CSNK2A2CSNK2A1MAOAMAOBRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132545-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2008-06-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132545-A1 | Certain chemical entities, compositions, and methods | MYLK, MYH2, MYH10 | CSNK2A2 595/4885CSNK2A1 835/4885MAOA 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.