Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5128116 | 0.87 | ALDH1A1 (0.49) | ALDH1A1HSD11B1TBXA2RKMT2A | |
| SCHEMBL493498 | 0.86 | TBXA2R (0.46) | ALDH1A1HSD11B1MMP1TBXA2RKMT2A | |
| SCHEMBL493486 | 0.84 | HTT (0.52) | ALDH1A1HTTHSD11B1MMP1KMT2A | |
| SCHEMBL493087 | 0.82 | TDP1 (0.43) | ALDH1A1KDM4EP2RY2PTGDR2GAA | |
| SCHEMBL493564 | 0.80 | TDP1 (0.36) | KDM4EP2RY2PTGDR2TBXA2RKMT2A | |
| SCHEMBL493617 | 0.80 | KMT2A (0.42) | ALDH1A1P2RY2GAATBXA2RKMT2A | |
| SCHEMBL5114277 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4EPTGDR2HTTKMT2A | |
| SCHEMBL493488 | 0.78 | NPSR1 (0.46) | ALDH1A1HTTKMT2A | |
| SCHEMBL5128990 | 0.78 | TBXA2R (0.36) | ALDH1A1TBXA2R | |
| SCHEMBL5131591 | 0.77 | P2RY2 (0.38) | ALDH1A1P2RY2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | ALDH1A1 1349/4885KDM4E 2178/4885P2RY2 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.