SCHEMBL4932972

SCHEMBL4932972

CCCC/N=C(\C)N(C)C

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
ALDH1A1 P00352 1/20 0.36
CES1 P23141 2/20 0.32
NOS1 P29475 1/20 0.32
DDAH1 O94760 1/20 0.31
CES2 O00748 1/20 0.31
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4932978 1.00 LMNA (0.41) LMNAMEN1KMT2AGRIN2DGRIN3B
SCHEMBL21478076 0.93 MEN1 (0.48) LMNAMEN1KMT2AGRIN2DGRIN3B
Bicarbonate SCHEMBL4935530 0.91 ALDH1A1 (0.40) LMNAMEN1KMT2AGRIN2DGRIN3B
SCHEMBL20718552 0.91 MEN1 (0.52) LMNAMEN1KMT2ASIGMAR1ALDH1A1
SCHEMBL4931847 0.91 MEN1 (0.52) LMNAMEN1KMT2ASIGMAR1ALDH1A1
SCHEMBL21523293 0.91 MEN1 (0.52) LMNAMEN1KMT2ASIGMAR1ALDH1A1
SCHEMBL4938498 0.91 MEN1 (0.52) LMNAMEN1KMT2ASIGMAR1ALDH1A1
SCHEMBL21523295 0.91 MEN1 (0.52) LMNAMEN1KMT2ASIGMAR1ALDH1A1
SCHEMBL4934095 0.91 MEN1 (0.52) LMNAMEN1KMT2ASIGMAR1ALDH1A1
SCHEMBL4938504 0.91 MEN1 (0.52) LMNAMEN1KMT2ASIGMAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651992-B1 METHOD FOR USE OF WATER WITH SWITCHABLE IONIC STRENGTH UNIV KINGSTON (CA) 2020-01-22 EP disclosed
US-10377647-B2 Systems and methods for use of water with switchable ionic strength Queen's University at Kingson (CA) 2019-08-13 US disclosed
US-20130087072-A1 Reversibly Switchable Surfactants and Methods of Use Thereof QUEEN'S UNIVERSITY AT KINGSTON (CA) 2013-04-11 US disclosed
US-8283385-B2 Emulsion polymerization; oil industry QUEEN'S UNIVERSITY AT KINGSTON (CA) 2012-10-09 US disclosed
US-20080197084-A1 Reversibly switchable surfactants and methods of use thereof QUEEN'S UNIVERSITY AT KINGSTON (CA) 2008-08-21 US disclosed
EP-1957434-A1 REVERSIBLY SWITCHABLE SURFACTANTS AND METHODS OF USE THEREOF QUEEN'S UNIVERSITY AT KINGSTON (CA) 2008-08-20 EP disclosed
US-20070242323-A1 Holographic recording composition and optical recording medium therewith FUJIFILM CORPORATION (JP) 2007-10-18 US disclosed
US-20070242323-A1 Holographic recording composition and optical recording medium therewith FUJIFILM CORPORATION (JP) 2007-10-18 US disclosed
WO-2007056859-A1 REVERSIBLY SWITCHABLE SURFACTANTS AND METHODS OF USE THEREOF QUEEN'S UNIVERSITY AT KINGSTON (CA) 2007-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080197084-A1 Reversibly switchable surfactants and methods of use thereof SGMS1, SGMS2, HDHD5 LMNA 292/4885MEN1 3941/4885KMT2A 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.