Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.40 |
| ▸ | THRA | P10827 | 8/20 | 0.39 |
| ▸ | THRB | P10828 | 8/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926378 | 0.91 | THRA (0.51) | FFAR4FFAR1THRATHRB | |
| SCHEMBL4926984 | 0.90 | THRA (0.38) | FFAR4FFAR1THRATHRBCRHR1 | |
| SCHEMBL4930725 | 0.87 | THRA (0.44) | FFAR4FFAR1THRATHRB | |
| SCHEMBL5717857 | 0.86 | THRA (0.39) | FFAR4FFAR1THRATHRBCRHR1 | |
| SCHEMBL4934279 | 0.85 | FFAR4 (0.41) | FFAR4FFAR1THRATHRB | |
| SCHEMBL4932819 | 0.85 | FFAR4 (0.44) | FFAR4FFAR1THRATHRB | |
| SCHEMBL4926674 | 0.85 | FFAR4 (0.40) | FFAR4FFAR1THRATHRBRXRA | |
| SCHEMBL5717918 | 0.83 | THRB (0.37) | THRATHRB | |
| SCHEMBL5112307 | 0.83 | FFAR4 (0.43) | FFAR4FFAR1THRATHRB | |
| SCHEMBL4926593 | 0.82 | FFAR4 (0.42) | FFAR4FFAR1THRATHRBRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | FFAR4 65/4885FFAR1 37/4885THRA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.