Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 18/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493414 | 0.98 | BDKRB1 (0.41) | BDKRB1AVPR1A | |
| SCHEMBL643969 | 0.86 | AVPR1B (0.41) | BDKRB1AVPR1A | |
| SCHEMBL492977 | 0.85 | BDKRB1 (0.36) | BDKRB1 | |
| SCHEMBL492598 | 0.83 | ACLY (0.37) | BDKRB1 | |
| SCHEMBL492742 | 0.81 | BDKRB1 (0.41) | BDKRB1MAPT | |
| SCHEMBL493310 | 0.80 | BDKRB1 (0.42) | BDKRB1MAPTAVPR1A | |
| SCHEMBL493412 | 0.80 | BDKRB1 (0.42) | BDKRB1MAPTAVPR1A | |
| SCHEMBL492675 | 0.79 | BDKRB1 (0.41) | BDKRB1MAPTAVPR1A | |
| SCHEMBL3406699 | 0.79 | BDKRB1 (0.40) | BDKRB1AVPR1A | |
| SCHEMBL493686 | 0.77 | BDKRB1 (0.41) | BDKRB1MAPTAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | claimed |
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | BDKRB1 1622/4885MAPT 1653/4885AVPR1A 537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.