Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 11/20 | 0.38 |
| ▸ | SLC9A3 | P48764 | 4/20 | 0.35 |
| ▸ | PTGIR | P43119 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493047 | 0.95 | BDKRB1 (0.37) | BDKRB1SLC9A3 | |
| SCHEMBL493893 | 0.94 | BDKRB1 (0.39) | BDKRB1SLC9A3PTGIRALDH1A1LMNA | |
| SCHEMBL493109 | 0.92 | SLC9A3 (0.35) | BDKRB1SLC9A3PTGIRALDH1A1LMNA | |
| SCHEMBL492489 | 0.91 | BDKRB1 (0.37) | BDKRB1SLC9A3PTGIR | |
| SCHEMBL492821 | 0.91 | BDKRB1 (0.44) | BDKRB1 | |
| SCHEMBL493432 | 0.90 | ALDH1A1 (0.38) | BDKRB1SLC9A3PTGIRALDH1A1LMNA | |
| SCHEMBL492577 | 0.90 | SLC9A3 (0.36) | BDKRB1SLC9A3PTGIR | |
| SCHEMBL493353 | 0.89 | BDKRB1 (0.52) | BDKRB1 | |
| SCHEMBL493431 | 0.88 | BDKRB1 (0.38) | BDKRB1SLC9A3PTGIR | |
| SCHEMBL492990 | 0.87 | UTS2R (0.36) | BDKRB1SLC9A3PTGIRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | claimed |
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| EP-2139851-A2 | SUBSTITUTED AMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2010-01-06 | — | — | EP | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| WO-2008131946-A2 | SUBSTITUTED AMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2008-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | BDKRB1 1622/4885SLC9A3 2717/4885PTGIR 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.