Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717852 | 0.91 | THRA (0.41) | EGLN1THRATHRBMRGPRX4AR | |
| SCHEMBL4926195 | 0.87 | CACNA1I (0.39) | THRATHRBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4931752 | 0.87 | THRB (0.47) | EGLN1THRATHRBMRGPRX4MEN1 | |
| SCHEMBL4929473 | 0.86 | THRA (0.36) | THRATHRBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4934084 | 0.86 | THRA (0.39) | THRATHRBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4934191 | 0.85 | EGLN1 (0.36) | EGLN1THRATHRBMRGPRX4MEN1 | |
| SCHEMBL4932995 | 0.85 | THRB (0.39) | EGLN1THRATHRBMRGPRX4MEN1 | |
| SCHEMBL4934946 | 0.84 | SMN1; SMN2 (0.41) | EGLN1THRATHRBMRGPRX4MEN1 | |
| SCHEMBL4934119 | 0.84 | THRA (0.52) | THRATHRBAR | |
| SCHEMBL4929633 | 0.83 | THRA (0.41) | EGLN1THRATHRBMRGPRX4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | EGLN1 2616/4885EGLN2 2270/4885THRA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.