Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 9/20 | 0.41 |
| ▸ | THRA | P10827 | 8/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718139 | 0.90 | MRGPRX4 (0.38) | MRGPRX4THRBTHRAMAPT | |
| SCHEMBL4929459 | 0.89 | FFAR1 (0.46) | MRGPRX4THRBTHRAFFAR1FFAR4 | |
| SCHEMBL5112522 | 0.89 | MRGPRX4 (0.41) | MRGPRX4THRBTHRAMAPTGPR35 | |
| SCHEMBL4932744 | 0.89 | THRB (0.41) | MRGPRX4THRBTHRAFFAR1FFAR4 | |
| SCHEMBL4931340 | 0.88 | THRB (0.51) | MRGPRX4THRBTHRA | |
| SCHEMBL4929467 | 0.87 | MRGPRX4 (0.40) | MRGPRX4THRBTHRAMAPT | |
| SCHEMBL5112473 | 0.87 | THRB (0.46) | MRGPRX4THRBTHRAGPR35 | |
| SCHEMBL5115981 | 0.86 | THRA (0.47) | MRGPRX4THRBTHRAGPR35 | |
| SCHEMBL4923532 | 0.84 | THRB (0.46) | MRGPRX4THRBTHRAMAPT | |
| SCHEMBL4930880 | 0.84 | MRGPRX4 (0.41) | MRGPRX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | MRGPRX4 119/4885THRB 4/4885THRA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.