Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 10/20 | 0.47 |
| ▸ | THRB | P10828 | 10/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.37 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5723352 | 0.91 | THRA (0.41) | THRATHRBMRGPRX4RORCKMT2A | |
| SCHEMBL5119314 | 0.90 | FFAR1 (0.42) | THRATHRBMRGPRX4RORCKMT2A | |
| SCHEMBL5110385 | 0.90 | THRB (0.47) | THRATHRBKMT2AMEN1SENP5 | |
| SCHEMBL5112522 | 0.88 | MRGPRX4 (0.41) | THRATHRBMRGPRX4RORCKMT2A | |
| SCHEMBL5112473 | 0.86 | THRB (0.46) | THRATHRBMRGPRX4RORCKMT2A | |
| SCHEMBL5110974 | 0.86 | THRA (0.51) | THRATHRBKMT2AMEN1SENP5 | |
| SCHEMBL4933997 | 0.86 | MRGPRX4 (0.42) | THRATHRBMRGPRX4GPR35 | |
| SCHEMBL5106743 | 0.85 | KMT2A (0.39) | THRATHRBMRGPRX4RORCKMT2A | |
| SCHEMBL5104963 | 0.85 | THRA (0.50) | THRATHRBKMT2AMEN1SENP5 | |
| SCHEMBL4932744 | 0.84 | THRB (0.41) | THRATHRBMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | KARO BIO AB (SE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | TSHR, TRHR, THRA | THRA 3/4885THRB 4/4885MRGPRX4 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.