Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3225639 | 0.87 | TLR8 (0.46) | HCAR2HCAR3TLR8CYP1A2MEN1 | |
| SCHEMBL4932341 | 0.82 | KDM4E (0.48) | KDM4ELMNAMAPTL3MBTL1GAA | |
| SCHEMBL25216352 | 0.78 | L3MBTL1 (0.40) | HCAR2L3MBTL1PLA2G4ACYP2C19 | |
| SCHEMBL245726 | 0.76 | TLR8 (0.49) | TLR8 | |
| SCHEMBL28218206 | 0.73 | CYP19A1 (0.37) | HCAR2CYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL28727319 | 0.73 | TLR8 (0.47) | HCAR2TLR8CYP1A2MEN1KMT2A | |
| SCHEMBL21564316 | 0.72 | HCAR2 (0.41) | HCAR2HCAR3CYP1A2KDM4EMEN1 | |
| SCHEMBL27602205 | 0.71 | BRD4 (0.50) | TLR8KDM4EALDH1A1TSHR | |
| Acetic Acid SCHEMBL1661241 | 0.70 | TLR8 (0.51) | TLR8ALDH1A1KMT2AAGTR1AGTR2 | |
| SCHEMBL5285380 | 0.69 | TLR8 (0.62) | TLR8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262066-A1 | Azole Derivatives as Cannabinoid CB1 Receptor Antagonists | GREEN CROSS CORPORATION (KR) | 2008-10-23 | — | — | US | disclosed |
| CN-101263122-A | 1, 2-diarylimidazoles useful as CB1 modulators | ASTRAZENECA AB (SE) | 2008-09-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262066-A1 | Azole Derivatives as Cannabinoid CB1 Receptor Antagonists | CNR1, CNR2, GPR119 | HCAR2 57/4885HCAR3 124/4885TLR8 1607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.