Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.38 |
| ▸ | THRB | P10828 | 8/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718054 | 0.94 | MEN1 (0.38) | THRATHRBDHODHMEN1KMT2A | |
| SCHEMBL4929570 | 0.91 | FFAR1 (0.35) | MEN1KMT2AENPP2NPC1RAB9A | |
| SCHEMBL4933385 | 0.89 | MEN1 (0.39) | THRATHRBDHODHMEN1KMT2A | |
| SCHEMBL4932240 | 0.87 | THRA (0.42) | THRATHRBDHODH | |
| SCHEMBL5718058 | 0.86 | MEN1 (0.36) | THRATHRBMEN1KMT2AENPP2 | |
| SCHEMBL5718015 | 0.86 | MEN1 (0.36) | THRATHRBMEN1KMT2AFFAR1 | |
| SCHEMBL5718319 | 0.84 | THRB (0.51) | THRATHRBDHODHENPP2ESR1 | |
| SCHEMBL4932962 | 0.84 | THRA (0.38) | THRATHRBDHODHFFAR1ESR1 | |
| SCHEMBL4922880 | 0.83 | THRB (0.40) | THRATHRBDHODHFFAR1ESR1 | |
| SCHEMBL4931798 | 0.83 | THRB (0.41) | THRATHRBDHODHFFAR1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | THRA 3/4885THRB 4/4885DHODH 4020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.