Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 5/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 6/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932565 | 0.91 | MRGPRX4 (0.41) | MRGPRX4MMEACECPA1ACE2 | |
| SCHEMBL5718015 | 0.88 | MEN1 (0.36) | THRATHRBMRGPRX4MMEACE | |
| SCHEMBL4934402 | 0.87 | THRA (0.38) | THRATHRBDHODH | |
| SCHEMBL4933385 | 0.87 | MEN1 (0.39) | THRATHRBDHODH | |
| SCHEMBL4934533 | 0.86 | THRB (0.47) | THRATHRBMRGPRX4S1PR1 | |
| SCHEMBL4932126 | 0.85 | THRA (0.42) | THRATHRBMRGPRX4MMEACE | |
| SCHEMBL4926344 | 0.85 | THRA (0.60) | THRATHRB | |
| SCHEMBL4930958 | 0.84 | THRA (0.44) | THRATHRBMRGPRX4MMEACE | |
| SCHEMBL4928651 | 0.84 | THRB (0.46) | THRATHRBMRGPRX4MMEACE | |
| SCHEMBL5718054 | 0.83 | MEN1 (0.38) | THRATHRBDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | THRA 3/4885THRB 4/4885MRGPRX4 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.