Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 17/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492742 | 0.91 | BDKRB1 (0.41) | BDKRB1 | |
| SCHEMBL493144 | 0.84 | BDKRB1 (0.40) | BDKRB1AVPR1BHPGD | |
| SCHEMBL493518 | 0.84 | PTGIR (0.36) | BDKRB1 | |
| SCHEMBL492872 | 0.83 | AVPR1B (0.40) | BDKRB1AVPR1B | |
| SCHEMBL3665067 | 0.80 | KMT2A (0.42) | — | |
| SCHEMBL492502 | 0.80 | BDKRB1 (0.39) | BDKRB1 | |
| SCHEMBL493122 | 0.80 | AVPR1A (0.40) | BDKRB1EPHX2 | |
| SCHEMBL645572 | 0.80 | AVPR1B (0.45) | BDKRB1AVPR1BEPHX2 | |
| SCHEMBL492956 | 0.80 | BDKRB1 (0.38) | BDKRB1AVPR1B | |
| SCHEMBL493601 | 0.76 | AVPR1B (0.37) | BDKRB1AVPR1BHPGDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | claimed |
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | BDKRB1 1622/4885AVPR1B 780/4885HPGD 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.