Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 7/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.36 |
| ▸ | SLC9A3 | P48764 | 6/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492816 | 0.90 | BDKRB1 (0.36) | BDKRB1SLC9A3KMT2A | |
| SCHEMBL3665067 | 0.88 | KMT2A (0.42) | PTGIRTHRBKMT2A | |
| SCHEMBL493266 | 0.87 | BDKRB1 (0.35) | BDKRB1SLC9A3KMT2A | |
| SCHEMBL493161 | 0.87 | FDFT1 (0.36) | PTGIRSLC9A3GRM5THRBKMT2A | |
| SCHEMBL493517 | 0.84 | BDKRB1 (0.41) | BDKRB1 | |
| SCHEMBL492844 | 0.82 | PTGIR (0.40) | PTGIRBDKRB1SLC9A3KMT2A | |
| SCHEMBL493592 | 0.82 | ALDH1A1 (0.37) | KMT2A | |
| SCHEMBL494025 | 0.81 | CXCR3 (0.36) | PTGIRBDKRB1SLC9A3 | |
| SCHEMBL493109 | 0.79 | SLC9A3 (0.35) | PTGIRBDKRB1SLC9A3GRM5 | |
| SCHEMBL493688 | 0.79 | PTGIR (0.37) | PTGIRBDKRB1SLC9A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | claimed |
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | PTGIR 121/4885BDKRB1 1622/4885SLC9A3 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.