Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4935269

CC(CCN)N1CCNCC1.N

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A3 Q01959 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM3 P20309 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GABBR2 O75899 1/20 0.30
GABBR1 Q9UBS5 1/20 0.30
CYP2D6 P10635 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9801277 0.98 SLC6A4 (0.32) SLC6A4SLC6A2SLC6A3CHRM5CHRM3
SCHEMBL9801549 0.86 SIGMAR1 (0.31) SLC6A4SLC6A2SLC6A3CHRM5CHRM3
SCHEMBL27094636 0.82
SCHEMBL2385429 0.82
SCHEMBL10305702 0.80 MEN1 (0.33) SLC6A4SLC6A2SLC6A3CHRM5CHRM3
SCHEMBL17916212 0.78 OPRL1 (0.40) SLC6A4SLC6A2SLC6A3CHRM5CHRM3
SCHEMBL18855182 0.78 CHRM5 (0.36) SLC6A4SLC6A2SLC6A3CHRM5CHRM3
SCHEMBL3822012 0.78 SIGMAR1 (0.36) SLC6A4SLC6A2SLC6A3CHRM5CHRM3
SCHEMBL3914623 0.78 GABBR2 (0.34) MEN1KMT2AGABBR2GABBR1CYP2D6
SCHEMBL28806945 0.78 SLC6A4 (0.30) SLC6A4SLC6A2SLC6A3CHRM5CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103351457-A Hydroxyalkylated polyalkylene polyamine composition, method for producing the same and method for producing polyurethane resin using the same TOSOH CORP 2013-10-16 CN claimed
CN-101048366-A Hydroxyalkylated polyalkylenepolyamine composition, method for producing same, and method for producing polyurethane resin using same TOSOH CORP (JP) 2007-10-03 CN claimed
CN-103351457-A Hydroxyalkylated polyalkylene polyamine composition, method for producing the same and method for producing polyurethane resin using the same TOSOH CORP 2013-10-16 CN disclosed
US-8222311-B2 Hydroxyalkylated polyalkylenepolyamine composition, method of producing the same and their use in polyurethanes TOSOH CORPORATION (JP) 2012-07-17 US disclosed
US-20080004362-A1 Hydroxyalkylated Polyalkylenepolyamine Composition, Method for Producing Same and Method for Producing Polyurethane Resin Using Such Hydroxyalkylated Polyalkylenepolyamine Composition TOSOCH CORPORATION (JP) 2008-01-03 US disclosed
CN-101048366-A Hydroxyalkylated polyalkylenepolyamine composition, method for producing same, and method for producing polyurethane resin using same TOSOH CORP (JP) 2007-10-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004362-A1 Hydroxyalkylated Polyalkylenepolyamine Composition, Method for Producing Same and Method for Producing Polyurethane Resin Using Such Hydroxyalkylated Polyalkylenepolyamine Composition SRM, HRH3, HNMT SLC6A4 3878/4885SLC6A2 2919/4885SLC6A3 3671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.