Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492795 | 0.93 | BDKRB1 (0.51) | BDKRB1 | |
| SCHEMBL492983 | 0.93 | BDKRB1 (0.40) | BDKRB1 | |
| SCHEMBL492502 | 0.91 | BDKRB1 (0.39) | BDKRB1 | |
| SCHEMBL493205 | 0.90 | BDKRB1 (0.49) | BDKRB1 | |
| SCHEMBL492638 | 0.89 | ALDH1A1 (0.45) | — | |
| SCHEMBL492295 | 0.88 | BDKRB1 (0.51) | BDKRB1 | |
| SCHEMBL493214 | 0.87 | BDKRB1 (0.43) | BDKRB1 | |
| SCHEMBL493577 | 0.86 | POLB (0.41) | — | |
| SCHEMBL493072 | 0.85 | ALDH1A1 (0.41) | — | |
| SCHEMBL493080 | 0.85 | BDKRB1 (0.42) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |
| EP-2139851-A2 | SUBSTITUTED AMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2010-01-06 | — | — | EP | claimed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | claimed |
| WO-2008131946-A2 | SUBSTITUTED AMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2008-11-06 | — | — | WO | claimed |
| WO-2013007371-A2 | KINETIC RESOLUTION OF CHIRAL AMINES | ETH ZURICH (CH) | 2013-01-17 | — | — | WO | disclosed |
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| EP-2231592-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | E. I. du Pont de Nemours and Company (US) | 2010-09-29 | — | — | EP | disclosed |
| EP-2139851-A2 | SUBSTITUTED AMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2010-01-06 | — | — | EP | disclosed |
| WO-2009085816-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-09 | — | — | WO | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| WO-2008131946-A2 | SUBSTITUTED AMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2008-11-06 | — | — | WO | disclosed |
| WO-2007089455-A1 | FLUOROALKENYL DERIVATIVES AS INSECTICIDES AND NEMATICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-08-09 | — | — | WO | disclosed |
| WO-2004020412-A1 | DIHYDROPYRIDINE DERIVATIVES FOR USE AS HUMAN NEUTROPHIL ELASTASE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2004-03-11 | — | — | WO | disclosed |
| WO-2003097734-A1 | RUBBER COMPOSITION FOR TYRE COMPRISING A COUPLING AGENT WITH POLYTHIOBENZOTHIAZYL FUNCTION | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2003-11-27 | — | — | WO | disclosed |
| WO-2003054075-A1 | RUBBER COMPOSITION FOR TYRE COMPRISING A COUPLING AGENT WITH POLYTHIOSUPLHENAMIDE FUNCTION | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2003-07-03 | — | — | WO | disclosed |
| WO-2003002653-A1 | RUBBER COMPOSITION FOR TYRE COMPRISING A COUPLING AGENT WITH POLYTHIOSULPHENAMIDE FUNCTION | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2003-01-09 | — | — | WO | disclosed |
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |
| EP-0028683-A1 | Antibiotic C-15003 PHO and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-05-20 | — | — | EP | disclosed |
| EP-0021173-A1 | Maytansinoids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | BDKRB1 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.