Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935760 | 0.98 | GRIK1 (0.45) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL3229578 | 0.98 | GRIK1 (0.45) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL4936597 | 0.87 | SLC1A2 (0.37) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL4936742 | 0.87 | SLC1A2 (0.37) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL17079705 | 0.84 | GRIK1 (0.42) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL1012232 | 0.82 | GPR84 (0.55) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL11425954 | 0.82 | GPR84 (0.55) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL8359696 | 0.80 | GRIK1 (0.53) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL9659765 | 0.79 | GPR84 (0.48) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL2035742 | 0.79 | GRIK1 (0.49) | GRIK1GRIK2SLC1A2SLC1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312080-A1 | Novel dioctatin derivatives and production process thereof | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312080-A1 | Novel dioctatin derivatives and production process thereof | AKR7A2, HDHD5, DECR1 | GRIK1 3638/4885GRIK2 3413/4885SLC1A2 3634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.