Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT1 | P54687 | 4/20 | 0.65 |
| ▸ | PYGL | P06737 | 10/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400081 | 0.81 | PYGL (0.61) | BCAT1PYGLEGFRNHERF1MEN1 | |
| SCHEMBL14089310 | 0.81 | BCAT1 (0.59) | BCAT1PYGLNHERF1 | |
| SCHEMBL18766925 | 0.79 | NHERF1 (0.79) | PYGLEGFRNHERF1 | |
| SCHEMBL4934951 | 0.78 | BCAT1 (0.58) | BCAT1PYGLEGFRNHERF1MEN1 | |
| SCHEMBL14089309 | 0.77 | BCAT1 (0.64) | BCAT1PYGLNHERF1MEN1KMT2A | |
| SCHEMBL4937303 | 0.77 | NHERF1 (0.57) | BCAT1PYGLEGFRNHERF1MEN1 | |
| SCHEMBL6405416 | 0.75 | BCAT1 (0.58) | BCAT1PYGLEGFRNHERF1MEN1 | |
| SCHEMBL14089311 | 0.75 | BCAT1 (0.66) | BCAT1NHERF1MEN1KMT2A | |
| SCHEMBL31058769 | 0.75 | NHERF1 (0.78) | PYGLNHERF1MEN1NPC1RAB9A | |
| SCHEMBL6399358 | 0.75 | KMT2A (0.66) | BCAT1PYGLEGFRNHERF1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188472-A1 | Indole-2-Carboxylic Acid Hydrazides | PROSIDION LIMITED (GB) | 2008-08-07 | — | — | US | disclosed |
| US-20080188472-A1 | Indole-2-Carboxylic Acid Hydrazides | PROSIDION LIMITED (GB) | 2008-08-07 | — | — | US | disclosed |
| US-20080188472-A1 | Indole-2-Carboxylic Acid Hydrazides | PROSIDION LIMITED (GB) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188472-A1 | Indole-2-Carboxylic Acid Hydrazides | PYGL, PYGM, CPT1A | BCAT1 194/4885PYGL 1/4885EGFR 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.