Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628396 | 0.77 | FYN (0.47) | FYNCRHR1HCAR3HCAR2 | |
| SCHEMBL6328 | 0.69 | CYP3A4 (0.38) | — | |
| Hydrochloric Acid SCHEMBL8876479 | 0.68 | CYP3A4 (0.36) | — | |
| SCHEMBL19031749 | 0.68 | CYP3A4 (0.36) | — | |
| SCHEMBL4784282 | 0.67 | FYN (0.41) | FYNCRHR1HCAR3HCAR2 | |
| SCHEMBL3394776 | 0.66 | TDP1 (0.34) | — | |
| SCHEMBL1248411 | 0.66 | TDP1 (0.34) | — | |
| SCHEMBL6445751 | 0.66 | CYP3A4 (0.38) | — | |
| SCHEMBL196880 | 0.66 | CYP3A4 (0.38) | — | |
| SCHEMBL21140560 | 0.66 | FYN (0.38) | FYNCRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015196-A1 | Imidazopyrazines, Imidazopyridines, and Imidazopyrimidines as Crf1 Receptor Ligands | NEUROGEN CORPORATION (US) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015196-A1 | Imidazopyrazines, Imidazopyridines, and Imidazopyrimidines as Crf1 Receptor Ligands | CRHR1, CRHR2, CRHBP | FYN 3789/4885CRHR1 1/4885HCAR3 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.