.Alpha.-Pyrrolidinononanophenone

.Alpha.-Pyrrolidinononanophenone

SCHEMBL4936225

CCCCCCCC(C(=O)c1ccccc1)N1CCCC1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 18/20 0.79
SLC6A2 P23975 15/20 0.79
SLC6A4 P31645 12/20 0.61
DRD3 P35462 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17655795 1.00 SLC6A3 (0.79) SLC6A3SLC6A2SLC6A4DRD3
SCHEMBL4931136 0.99 SLC6A3 (0.81) SLC6A3SLC6A2SLC6A4DRD3
Hydrochloric Acid SCHEMBL29398571 0.97 SLC6A3 (0.79) SLC6A3SLC6A2SLC6A4DRD3
SCHEMBL21271156 0.94 SLC6A3 (0.83) SLC6A3SLC6A2SLC6A4
SCHEMBL27098434 0.93 SLC6A3 (0.81) SLC6A3SLC6A2SLC6A4
SCHEMBL27098438 0.93 SLC6A3 (0.81) SLC6A3SLC6A2SLC6A4
SCHEMBL4936204 0.88 SLC6A3 (1.00) SLC6A3SLC6A2SLC6A4
Hydrochloric Acid SCHEMBL30624700 0.87 SLC6A3 (0.97) SLC6A3SLC6A2SLC6A4
SCHEMBL17661659 0.86 SLC6A3 (0.80) SLC6A3SLC6A2SLC6A4
SCHEMBL27098435 0.83 SLC6A3 (0.69) SLC6A3SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-222761821-U Transformer insulating oil seepage overhauls device 广西送变电建设有限责任公司 2025-04-15 CN claimed
CN-118846122-B Nanoparticle for targeted regulation of meningeal lymphatic system as well as preparation method and application thereof 海南大学 2025-04-04 CN claimed
CN-119199463-B IGBT internal defect positioning method and device based on current rising transient process 华北电力科学研究院有限责任公司 2025-02-28 CN claimed
CN-119199463-A IGBT internal defect positioning method and device based on current rising transient process 华北电力科学研究院有限责任公司 2024-12-27 CN claimed
CN-118846122-A Nanoparticle for targeted regulation of meningeal lymphatic system as well as preparation method and application thereof 海南大学 2024-10-29 CN claimed
CN-118468764-A Temperature criterion setting method for identifying IGBT aging state 北京交通大学 2024-08-09 CN claimed
US-20230364086-A1 COMBINATION THERAPIES WITH EHMT2 INHIBITORS Epizyme, Inc. 2023-11-16 US claimed
CN-116794478-A Thyristor junction temperature extraction method based on thyristor switching delay time 国网安徽省电力有限公司电力科学研究院 2023-09-22 CN claimed
CN-116736063-A IGBT state evaluation method based on weighted LSTM 安徽大学 2023-09-12 CN claimed
US-20080234498-A1 Pyrovalerone Analogues and Therapeutic Uses Thereof PRESIDENT AND FELLOW OF HARVARD COLLEGE (US) 2008-09-25 US claimed
EP-1670755-A4 PYROVALERONE ANALOGS AND THERAPEUTIC USES THEREOF HARVARD COLLEGE (US) 2007-02-28 EP claimed
EP-1670755-A2 PYROVALERONE ANALOGS AND THERAPEUTIC USES THEREOF President And Fellows of Harvard College (US) 2006-06-21 EP claimed
WO-2005034878-A2 PYROVALERONE ANALOGS AND THERAPEUTIC USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2005-04-21 WO claimed
US-20260090989-A1 LIPID NANOPARTICLE mRNA VACCINES CureVac SE (DE) 2026-04-02 US disclosed
US-12576040-B2 Ionizable lipids and methods of manufacture and use thereof THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2026-03-17 US disclosed
US-12571799-B2 Biomarkers for determining the efficacy of immune checkpoint inhibitors ONO PHARMACEUTICAL CO., LTD. (JP) 2026-03-10 US disclosed
US-20080234498-A1 Pyrovalerone Analogues and Therapeutic Uses Thereof PRESIDENT AND FELLOW OF HARVARD COLLEGE (US) 2008-09-25 US disclosed
EP-1670755-A4 PYROVALERONE ANALOGS AND THERAPEUTIC USES THEREOF HARVARD COLLEGE (US) 2007-02-28 EP disclosed
EP-1670755-A2 PYROVALERONE ANALOGS AND THERAPEUTIC USES THEREOF President And Fellows of Harvard College (US) 2006-06-21 EP disclosed
WO-2005034878-A2 PYROVALERONE ANALOGS AND THERAPEUTIC USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2005-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080234498-A1 Pyrovalerone Analogues and Therapeutic Uses Thereof SLC6A2, SLC6A4, SLC6A3 SLC6A3 3/4885SLC6A2 1/4885SLC6A4 2/4885
US-12576040-B2 Ionizable lipids and methods of manufacture and use thereof NPC1L1, NSUN3, CETP SLC6A3 3267/4885SLC6A2 3726/4885SLC6A4 3672/4885
US-20230364086-A1 COMBINATION THERAPIES WITH EHMT2 INHIBITORS EHMT2, BHMT, SHMT2 SLC6A3 2300/4885SLC6A2 941/4885SLC6A4 1826/4885
US-20260090989-A1 LIPID NANOPARTICLE mRNA VACCINES RNMT, NSUN3, SARNP SLC6A3 2107/4885SLC6A2 1879/4885SLC6A4 2692/4885
US-12571799-B2 Biomarkers for determining the efficacy of immune checkpoint inhibitors CD274, PDCD1, PDCD1LG2 SLC6A3 3870/4885SLC6A2 3475/4885SLC6A4 3933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.