Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360388 | 0.86 | SLC9A1 (0.46) | SLC9A1ALDH1A1HSD17B10CFTRKDM4E | |
| SCHEMBL3361482 | 0.85 | SLC9A1 (0.45) | SLC9A1ALDH1A1HSD17B10CFTRKDM4E | |
| SCHEMBL30501678 | 0.85 | SMN1; SMN2 (0.66) | SLC9A1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL23091228 | 0.85 | SLC9A1 (0.55) | SLC9A1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL30501694 | 0.85 | SLC9A1 (0.55) | SLC9A1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL23091170 | 0.85 | SMN1; SMN2 (0.66) | SLC9A1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL4946365 | 0.82 | ALDH1A1 (0.61) | SLC9A1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL7064007 | 0.81 | SLC9A1 (0.65) | SLC9A1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL4946572 | 0.81 | RAB9A (0.67) | SLC9A1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL4937754 | 0.81 | ALDH1A1 (0.74) | SLC9A1ALDH1A1HSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351843-B2 | Furancarbonylguanidine derivatives, their preparation and pharmaceutical compositions containing them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-04-01 | — | — | US | disclosed |
| US-20070299131-A1 | Furancarbonylguanidine Derivatives, Their Preparation and Pharmaceutical Compositions Containing Them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-12-27 | — | — | US | disclosed |
| EP-1697335-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063727-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-07-14 | — | — | WO | disclosed |
| US-4773927-A | ORTHO-FURANYL-,-THIENYL- OR -PYRROLYL-BENZENE SULFONYLUREAS | E. I DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-27 | — | — | US | disclosed |
| US-4699648-A | HERBICIDE, PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-13 | — | — | US | disclosed |
| EP-0085476-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-22 | — | — | EP | disclosed |
| US-4592775-A | Containing hetero ring substitution | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-06-03 | — | — | US | disclosed |
| US-4460401-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0085476-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299131-A1 | Furancarbonylguanidine Derivatives, Their Preparation and Pharmaceutical Compositions Containing Them | SLC9A1, NHERF1, SLC5A1 | SLC9A1 1/4885ALDH1A1 297/4885HSD17B10 1301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.