Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | EBP | Q15125 | 1/20 | 0.54 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750626 | 0.85 | PKM (0.59) | PKMALDH1A1KDM4EHTTPOLB | |
| SCHEMBL4750625 | 0.85 | PKM (0.59) | PKMALDH1A1KDM4EHTTPOLB | |
| SCHEMBL8185779 | 0.85 | EBP (0.63) | PKMALDH1A1KDM4EHTTPOLB | |
| SCHEMBL13818486 | 0.85 | EBP (0.63) | PKMALDH1A1KDM4EHTTPOLB | |
| SCHEMBL6882681 | 0.85 | EBP (0.63) | PKMALDH1A1KDM4EHTTPOLB | |
| SCHEMBL265385 | 0.83 | PKM (0.57) | PKMALDH1A1KDM4EHTTPOLB | |
| SCHEMBL3235046 | 0.83 | PKM (0.57) | PKMALDH1A1KDM4EHTTPOLB | |
| SCHEMBL4516709 | 0.83 | PKM (0.57) | PKMALDH1A1KDM4EHTTPOLB | |
| SCHEMBL28847667 | 0.83 | PKM (0.57) | PKMALDH1A1KDM4EHTTPOLB | |
| SCHEMBL14044222 | 0.83 | PKM (0.57) | PKMALDH1A1KDM4EHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | PKM 1161/4885ALDH1A1 1349/4885KDM4E 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.