Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934552 | 0.98 | LMNA (0.33) | LMNA | |
| SCHEMBL4930840 | 0.98 | LMNA (0.33) | LMNA | |
| SCHEMBL4938355 | 0.98 | LMNA (0.33) | LMNA | |
| SCHEMBL4938720 | 0.96 | LMNA (0.32) | LMNA | |
| SCHEMBL4938362 | 0.96 | LMNA (0.32) | LMNA | |
| SCHEMBL10825969 | 0.84 | LMNA (0.43) | LMNA | |
| SCHEMBL16669165 | 0.78 | — | — | |
| SCHEMBL4933973 | 0.74 | LMNA (0.40) | LMNA | |
| SCHEMBL5137828 | 0.74 | LMNA (0.35) | LMNA | |
| SCHEMBL30891614 | 0.74 | TSHR (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150119848-A1 | METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2015-04-30 | — | — | US | claimed |
| EP-3629928-B1 | METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE | THE UNIV OF TENNESSEE RESEARCH FOUNDATION (US) | 2025-11-05 | — | — | EP | disclosed |
| US-11686722-B2 | Compositions and methods to detect molecules in a sample | INFUSENSE CORP. (US) | 2023-06-27 | — | — | US | disclosed |
| US-11375929-B2 | Method and device for detection of bioavailable drug concentration in a fluid sample | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2022-07-05 | — | — | US | disclosed |
| US-20190331656-A1 | COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE | INFUSENSE CORP. | 2019-10-31 | — | — | US | disclosed |
| EP-3555609-A1 | COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE | Infusense Corp. (US) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018112458-A1 | COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE | INFUSENSE CORP. (US) | 2018-06-21 | — | — | WO | disclosed |
| US-9983162-B2 | Method and device for detection of bioavailable drug concentration | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2018-05-29 | — | — | US | disclosed |
| US-20150119848-A1 | METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2015-04-30 | — | — | US | disclosed |