Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934552 | 0.98 | LMNA (0.33) | LMNA | |
| SCHEMBL4938355 | 0.98 | LMNA (0.33) | LMNA | |
| SCHEMBL4930840 | 0.98 | LMNA (0.33) | LMNA | |
| SCHEMBL4938720 | 0.96 | LMNA (0.32) | LMNA | |
| Potassium Ion SCHEMBL16669384 | 0.96 | LMNA (0.32) | LMNA | |
| SCHEMBL10825969 | 0.84 | LMNA (0.43) | LMNA | |
| SCHEMBL16669165 | 0.78 | — | — | |
| SCHEMBL4932994 | 0.76 | — | — | |
| SCHEMBL4933973 | 0.74 | LMNA (0.40) | LMNA | |
| SCHEMBL30891614 | 0.74 | TSHR (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11193915-B2 | Composite material for the detection of chemical species | INSTITUT NATIONAL D'OPTIQUE (CA) | 2021-12-07 | — | — | US | claimed |
| US-20190017978-A1 | COMPOSITE MATERIAL FOR THE DETECTION OF CHEMICAL SPECIES | INSTITUT NATIONAL D'OPTIQUE (CA) | 2019-01-17 | — | — | US | claimed |
| WO-2017088069-A1 | COMPOSITE MATERIAL FOR THE DETECTION OF CHEMICAL SPECIES | INSTITUT NATIONAL D'OPTIQUE (CA) | 2017-06-01 | — | — | WO | claimed |
| US-8845905-B2 | Polypyrrole copolymer nanoparticles-based compositions and methods for detecting lead ions | TONGJI UNIVERSITY (CN) | 2014-09-30 | — | — | US | claimed |
| US-20140183062-A1 | POLYPYRROLE COPOLYMER NANOPARTICLES-BASED COMPOSITIONS AND METHODS FOR DETECTING LEAD LIONS | TONGJI UNIVERSITY (CN) | 2014-07-03 | — | — | US | claimed |
| WO-2013138978-A1 | POLYPYRROLE COPOLYMER NANOPARTICLES-BASED COMPOSITIONS AND METHODS FOR DETECTING LEAD IONS | TONGJI UNIVERSITY (CN) | 2013-09-26 | — | — | WO | claimed |
| US-11193915-B2 | Composite material for the detection of chemical species | INSTITUT NATIONAL D'OPTIQUE (CA) | 2021-12-07 | — | — | US | disclosed |
| US-20190017978-A1 | COMPOSITE MATERIAL FOR THE DETECTION OF CHEMICAL SPECIES | INSTITUT NATIONAL D'OPTIQUE (CA) | 2019-01-17 | — | — | US | disclosed |
| WO-2017088069-A1 | COMPOSITE MATERIAL FOR THE DETECTION OF CHEMICAL SPECIES | INSTITUT NATIONAL D'OPTIQUE (CA) | 2017-06-01 | — | — | WO | disclosed |
| US-8845905-B2 | Polypyrrole copolymer nanoparticles-based compositions and methods for detecting lead ions | TONGJI UNIVERSITY (CN) | 2014-09-30 | — | — | US | disclosed |
| US-20140183062-A1 | POLYPYRROLE COPOLYMER NANOPARTICLES-BASED COMPOSITIONS AND METHODS FOR DETECTING LEAD LIONS | TONGJI UNIVERSITY (CN) | 2014-07-03 | — | — | US | disclosed |
| US-8765060-B2 | Chemical sensor | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-07-01 | — | — | US | disclosed |
| WO-2013138978-A1 | POLYPYRROLE COPOLYMER NANOPARTICLES-BASED COMPOSITIONS AND METHODS FOR DETECTING LEAD IONS | TONGJI UNIVERSITY (CN) | 2013-09-26 | — | — | WO | disclosed |
| US-20080293997-A1 | Chemical Sensor | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-11-27 | — | — | US | disclosed |
| EP-1888330-A2 | CHEMICAL SENSOR | The Regents of the University of Minnesota (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006127963-A2 | CHEMICAL SENSOR | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2006-11-30 | — | — | WO | disclosed |