SCHEMBL4938360

SCHEMBL4938360

CS(=O)(=O)c1ccc(-c2ccc(F)cc2)c(C(=O)N2CCN(c3ccc(N)cc3F)CC2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 20/20 1.00
GPR55 Q9Y2T6 2/20 1.00
KCNH2 Q12809 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5025383 0.92 SLC6A9 (0.85) SLC6A9GPR55KCNH2
SCHEMBL4937951 0.88 SLC6A9 (0.78) SLC6A9GPR55KCNH2
SCHEMBL8259226 0.88 SLC6A9 (0.85) SLC6A9GPR55KCNH2
SCHEMBL4427067 0.88 SLC6A9 (0.86) SLC6A9GPR55
SCHEMBL4435029 0.87 SLC6A9 (0.78) SLC6A9GPR55KCNH2
SCHEMBL4948286 0.87 SLC6A9 (0.79) SLC6A9GPR55
SCHEMBL4424389 0.87 SLC6A9 (0.78) SLC6A9GPR55KCNH2
SCHEMBL4940865 0.87 SLC6A9 (0.77) SLC6A9GPR55KCNH2
SCHEMBL4435110 0.86 SLC6A9 (0.76) SLC6A9GPR55KCNH2
SCHEMBL4434079 0.86 SLC6A9 (0.90) SLC6A9GPR55KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021243093-A1 METHODS AND COMPOSITIONS FOR TREATING AND RECOVERING FORM VIRAL INFECTIONS IMMUNOFLEX THERAPEUTICS INC. (CA) 2021-12-02 WO disclosed
US-20210369661-A1 METHODS AND COMPOSITIONS FOR TREATING AND RECOVERING FROM VIRAL INFECTIONS IMMUNOFLEX THERAPEUTICS INC. (CA) 2021-12-02 US disclosed
US-20080255144-A1 Acylated Piperidines as Glycine Transporter Inhibitors GLAXO GROUP LIMITED 2008-10-16 US disclosed
US-20080255144-A1 Acylated Piperidines as Glycine Transporter Inhibitors GLAXO GROUP LIMITED 2008-10-16 US disclosed
US-20080255144-A1 Acylated Piperidines as Glycine Transporter Inhibitors GLAXO GROUP LIMITED 2008-10-16 US disclosed
EP-1858869-A1 ACYLATED PIPERIDINES AS GLYCINE TRANSPORTER INHIBITORS GLAXO GROUP LIMITED (GB) 2007-11-28 EP disclosed
WO-2006094842-A1 ACYLATED PIPERIDIHES AS GLYCINE TRANSPORTER INHIBITORS GLAXO GROUP LIMITED (GB) 2006-09-14 WO disclosed
WO-2006094842-A1 ACYLATED PIPERIDIHES AS GLYCINE TRANSPORTER INHIBITORS GLAXO GROUP LIMITED (GB) 2006-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080255144-A1 Acylated Piperidines as Glycine Transporter Inhibitors SLC1A1, SLC6A7, SLC1A2 SLC6A9 9/4885GPR55 485/4885KCNH2 562/4885
US-20210369661-A1 METHODS AND COMPOSITIONS FOR TREATING AND RECOVERING FROM VIRAL INFECTIONS IFNG, CD4, MAVS SLC6A9 4835/4885GPR55 2713/4885KCNH2 3057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.