SCHEMBL4939618

SCHEMBL4939618

CCc1ccccc1-c1ccc(C(=O)NC(=N)N)o1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.61
S1PR4 O95977 2/20 0.49
ALDH1A1 P00352 5/20 0.45
KDM4E B2RXH2 5/20 0.45
HPGD P15428 3/20 0.45
MAPT P10636 2/20 0.45
LMNA P02545 2/20 0.45
MAPK1 P28482 2/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 3/20 0.44
NPC1 O15118 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4941515 0.83 ALDH1A1 (0.66) SLC9A1S1PR4ALDH1A1KDM4EHPGD
SCHEMBL4946626 0.82 SLC9A1 (0.58) SLC9A1ALDH1A1KDM4EHPGDMAPT
SCHEMBL4952806 0.81 RAB9A (0.60) SLC9A1ALDH1A1KDM4EHPGDMAPT
SCHEMBL4942987 0.81 RAB9A (0.63) SLC9A1ALDH1A1KDM4EHPGDMAPT
SCHEMBL4942893 0.80 ALDH1A1 (0.55) SLC9A1S1PR4ALDH1A1KDM4EHPGD
SCHEMBL4937731 0.79 SLC9A1 (0.61) SLC9A1S1PR4ALDH1A1KDM4EHPGD
SCHEMBL4948246 0.79 RAB9A (0.54) SLC9A1S1PR4ALDH1A1KDM4EHPGD
SCHEMBL4946448 0.78 SLC9A1 (0.64) SLC9A1ALDH1A1KDM4EHPGDMAPT
SCHEMBL4939604 0.78 ALDH1A1 (0.56) SLC9A1ALDH1A1KDM4EHPGDMAPT
SCHEMBL4937608 0.77 SLC9A1 (0.62) SLC9A1S1PR4ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7351843-B2 Furancarbonylguanidine derivatives, their preparation and pharmaceutical compositions containing them KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-04-01 US disclosed
US-20070299131-A1 Furancarbonylguanidine Derivatives, Their Preparation and Pharmaceutical Compositions Containing Them KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2007-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070299131-A1 Furancarbonylguanidine Derivatives, Their Preparation and Pharmaceutical Compositions Containing Them SLC9A1, NHERF1, SLC5A1 SLC9A1 1/4885S1PR4 2223/4885ALDH1A1 297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.