Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | SHBG | P04278 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21807754 | 1.00 | PGR (0.47) | PGRARCYP19A1SHBGALDH1A1 | |
| SCHEMBL9541157 | 0.87 | PGR (0.47) | PGRARCYP19A1SHBGALDH1A1 | |
| SCHEMBL5700334 | 0.85 | CYP19A1 (0.46) | PGRARCYP19A1SHBGALDH1A1 | |
| SCHEMBL5700181 | 0.85 | CYP19A1 (0.46) | PGRARCYP19A1SHBGALDH1A1 | |
| SCHEMBL5700038 | 0.83 | CYP19A1 (0.44) | PGRARCYP19A1SHBGALDH1A1 | |
| SCHEMBL7125405 | 0.79 | CYP19A1 (0.72) | PGRARCYP19A1SHBGHTR2B | |
| SCHEMBL151284 | 0.77 | SHBG (0.59) | ARCYP19A1SHBGALDH1A1LMNA | |
| SCHEMBL931136 | 0.77 | SHBG (0.59) | ARCYP19A1SHBGALDH1A1LMNA | |
| SCHEMBL9541205 | 0.76 | PGR (0.41) | PGRARCYP19A1SHBGALDH1A1 | |
| SCHEMBL9541223 | 0.75 | PDK1 (0.43) | PGRARSHBGALDH1A1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238310-A1 | MODULATION OF SEX STEROID HORMONE PRODUCTION AND ACTIVITY FOR TREATING AND PREVENTING HERNIAS | NORTHWESTERN UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
| US-20210346385-A1 | TASTE-MASKED DOSAGE FORMS | DEEP OCEAN CAPITAL MANAGEMENT LP | 2021-11-11 | — | — | US | disclosed |
| US-20210283144-A1 | MODULATION OF SEX STEROID HORMONE PRODUCTION AND ACTIVITY FOR TREATING AND PREVENTING HERNIAS | NORTHWESTERN UNIVERSITY | 2021-09-16 | — | — | US | disclosed |
| WO-2020061584-A1 | TASTE-MASKED DOSAGE FORMS | MSB HOLDINGS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| US-20150152348-A1 | SYSTEMS AND METHODS FOR COLLECTING, TRANSPORTING AND REPURPOSING OR DESTROYING UNUSED PHARMACEUTICALS | SHARPS COMPLIANCE, INC. OF TEXAS | 2015-06-04 | — | — | US | disclosed |
| US-20080207601-A1 | Methods of and Compositions For the Prevention of Anxiety, Substance Abuse, and Dependence | HYTHIAM , INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080075772-A1 | PHARMACEUTICAL COMPOSITIONS HAVING NOVEL SCORING PATTERNS AND METHODS OF USING THOSE COMPOSITIONS | ACCU-BREAK TECHNOLOGIES, INC. | 2008-03-27 | — | — | US | disclosed |
| US-20040002483-A1 | Use of ester and ether derivatives of 4-hydroxy-19-norandrosterone to increase the level of the anabolic/androgenic hormone 4-hydroxy-19-nortestosterone in humans | Paternoster, Mr. Vince | 2004-01-01 | — | — | US | disclosed |
| US-20030199486-A1 | Ester and ether derivatives of 4-hydroxy-19-nortestosterone and a method for the regulation of athletic function in humans | NUTRI SPORT PHARMACAL, INC. (US) | 2003-10-23 | — | — | US | disclosed |