Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | STS | P08842 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522842 | 0.80 | CYP19A1 (0.51) | PGRSHBGALDH1A1NR3C1ADRA1A | |
| SCHEMBL11522845 | 0.80 | CYP19A1 (0.51) | PGRSHBGALDH1A1NR3C1ADRA1A | |
| SCHEMBL9541157 | 0.76 | PGR (0.47) | PGRARSHBGALDH1A1NR3C1 | |
| SCHEMBL21807754 | 0.76 | PGR (0.47) | PGRARSHBGALDH1A1NR3C1 | |
| SCHEMBL4940396 | 0.76 | PGR (0.47) | PGRARSHBGALDH1A1NR3C1 | |
| SCHEMBL9124485 | 0.75 | SHBG (0.41) | PGRARSHBGALDH1A1NR3C1 | |
| SCHEMBL9124492 | 0.75 | SHBG (0.41) | PGRARSHBGALDH1A1NR3C1 | |
| SCHEMBL9127322 | 0.73 | SHBG (0.53) | PGRARSHBGALDH1A1NR3C1 | |
| SCHEMBL9127331 | 0.73 | SHBG (0.53) | PGRARSHBGALDH1A1NR3C1 | |
| SCHEMBL9541167 | 0.72 | CYP19A1 (0.40) | PGRSHBGALDH1A1NR3C1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |