SCHEMBL4940478

SCHEMBL4940478

C=C(C)C(=O)NCCCNC(=O)CCl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
FAAH O00519 3/20 0.38
TSHR P16473 1/20 0.37
KDM4E B2RXH2 3/20 0.37
MAPK1 P28482 1/20 0.37
HIF1A Q16665 1/20 0.37
CASP2 P42575 1/20 0.34
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
POLB P06746 1/20 0.33
TGFBR1 P36897 1/20 0.32
NAAA Q02083 1/20 0.32
LMNA P02545 1/20 0.32
TEAD1 P28347 1/20 0.32
YAP1 P46937 1/20 0.32
TEAD4 Q15561 1/20 0.32
TEAD2 Q15562 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9148100 0.92 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2MEN1KMT2AFAAH
SCHEMBL632876 0.87 KDM4E (0.46) ALDH1A1MEN1KMT2AKDM4EMAPK1
SCHEMBL8943380 0.87 FAAH (0.46) ALDH1A1SMN1; SMN2MEN1KMT2AFAAH
SCHEMBL8362379 0.85 SMN1; SMN2 (0.39) ALDH1A1SMN1; SMN2MEN1KMT2AFAAH
SCHEMBL16309325 0.85 KDM4E (0.44) ALDH1A1MEN1KMT2AKDM4EMAPK1
SCHEMBL16309303 0.84 FAAH (0.46) SMN1; SMN2MEN1KMT2AFAAHTSHR
SCHEMBL219655 0.84 MEN1 (0.40) ALDH1A1SMN1; SMN2MEN1KMT2AFAAH
SCHEMBL7857220 0.83 FAAH (0.44) ALDH1A1SMN1; SMN2MEN1KMT2AFAAH
SCHEMBL907569 0.83 KDM4E (0.52) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL820163 0.82 MEN1 (0.39) ALDH1A1SMN1; SMN2MEN1KMT2AFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5429931-A Oxidized NAD, alcohol dehydrogenase, acrylic copolymer EASTMAN KODAK COMPANY (US) 1995-07-04 US claimed
EP-0419652-B1 POLYMERIC ELECTROPHORESIS MEDIA EASTMAN KODAK CO (US) 1994-01-05 EP claimed
US-5212253-A Electrophoresis element comprising a polymer containing a haloacetamido group EASTMAN KODAK COMPANY (US) 1993-05-18 US claimed
EP-0419652-A1 POLYMERIC ELECTROPHORESIS MEDIA. EASTMAN KODAK CO (US) 1991-04-03 EP claimed
WO-1990012820-A1 POLYMERIC ELECTROPHORESIS MEDIA EASTMAN KODAK COMPANY (US) 1990-11-01 WO claimed
EP-0340653-A2 Kit for electrophoresis gel medium EASTMAN KODAK COMPANY (US) 1989-11-08 EP claimed
US-20080114451-A1 RETENTION COATINGS FOR DELIVERY SYSTEMS Surmodics Coatings, LLC 2008-05-15 US disclosed
US-20080114451-A1 RETENTION COATINGS FOR DELIVERY SYSTEMS Surmodics Coatings, LLC 2008-05-15 US disclosed
US-20080114451-A1 RETENTION COATINGS FOR DELIVERY SYSTEMS Surmodics Coatings, LLC 2008-05-15 US disclosed
US-20040044404-A1 Retention coatings for delivery systems Surmodics Coatings, LLC 2004-03-04 US disclosed
EP-0626580-B1 Multilayer analytical element containing niacinamide and method for the determination of ethanol JOHNSON & JOHNSON CLIN DIAG (US) 1999-11-03 EP disclosed
EP-0476102-B1 CONTROL OF PRESSURE-FOG WITH GELATIN-GRAFTED AND CASE-HARDENED GELATIN-GRAFTED SOFT POLYMER LATEX PARTICLES EASTMAN KODAK CO (US) 1998-07-22 EP disclosed
EP-0478735-B1 USE OF GELATIN-GRAFTED AND CASE-HARDENED GELATIN-GRAFTED POLYMER PARTICLES FOR RELIEF FROM PRESSURE SENSITIVITY OF PHOTOGRAPHIC PRODUCTS EASTMAN KODAK CO (US) 1997-10-08 EP disclosed
WO-1990012820-A1 POLYMERIC ELECTROPHORESIS MEDIA EASTMAN KODAK COMPANY (US) 1990-11-01 WO disclosed
WO-1990009593-A1 METHOD AND KIT FOR DETERMINATION OF HERPES SIMPLEX VIRAL ANTIGEN BY DIRECT BINDING TO POLYMERIC PARTICLES EASTMAN KODAK COMPANY (US) 1990-08-23 WO disclosed
US-4948480-A DISSOLVING ACRYLAMIDE COPOLYMER IN WATER, ADDING BUFFER, ADDING CROSSLINKING AGENT FROM SEPARATE PACKAGE EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed
EP-0347137-A2 Microporous article having a stabilized specific binding reagent, a method for its use and a diagnostic test kit EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-12-20 EP disclosed
EP-0340653-A2 Kit for electrophoresis gel medium EASTMAN KODAK COMPANY (US) 1989-11-08 EP disclosed
WO-1989009939-A1 COMPOSITIONS, DIAGNOSTIC KIT AND METHOD FOR RAPID DETECTION OF ANTIBODIES EASTMAN KODAK COMPANY (US) 1989-10-19 WO disclosed
EP-0337785-A1 Diagnostic kit and method for rapid detection of antibodies Johnson & Johnson Clinical Diagnostics, Inc. (US) 1989-10-18 EP disclosed