SCHEMBL8943380

SCHEMBL8943380

C=C(C)C(=O)NCCCNC(=O)CCCl

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.46
CASP2 P42575 1/20 0.43
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TSHR P16473 1/20 0.38
POLB P06746 1/20 0.37
NAAA Q02083 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HPGD P15428 2/20 0.36
MAPT P10636 1/20 0.36
ALOX12 P18054 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8426209 0.93 FAAH (0.42) FAAHCASP2ALDH1A1SMN1; SMN2TSHR
SCHEMBL16309303 0.87 FAAH (0.46) FAAHCASP2SMN1; SMN2TSHRPOLB
SCHEMBL4940478 0.87 ALDH1A1 (0.56) FAAHCASP2ALDH1A1SMN1; SMN2TSHR
SCHEMBL4199320 0.87 FAAH (0.35) FAAHCASP2ALDH1A1SMN1; SMN2POLB
SCHEMBL7857220 0.83 FAAH (0.44) FAAHALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL632876 0.82 KDM4E (0.46) ALDH1A1MEN1KMT2ATDP1
SCHEMBL16798934 0.82 CASP2 (0.52) FAAHCASP2NAAAHPGDCNR1
SCHEMBL16798851 0.81 ADRA1A (0.50) FAAHTSHRMEN1KMT2AMAPT
SCHEMBL6135404 0.81 FAAH (0.57) FAAHCASP2NAAAHPGDCNR1
SCHEMBL16799467 0.81 TSHR (0.50) SMN1; SMN2TSHRMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5518877-A POLYPEPTIDE-ADDITION POLYMER AGFA-GEVAERT AG (DE) 1996-05-21 US disclosed
EP-0337785-B2 Diagnostic kit and method for rapid detection of antibodies JOHNSON & JOHNSON CLIN DIAG (US) 1996-03-13 EP disclosed
EP-0666498-A2 Silver halide photographic material Agfa-Gevaert AG (DE) 1995-08-09 EP disclosed
EP-0468584-B1 Copolymers containing polyoxyalkylene side chains EASTMAN KODAK CO (US) 1995-01-18 EP disclosed
US-5374516-A Covalently attached to polymer particles of ethylenically unsaturated monomers with reactive alkylsulfonyl or halogen groups; detecting hormones, drugs, steroids in urine, blood, saliva EASTMAN KODAK COMPANY (US) 1994-12-20 US disclosed
EP-0347137-B1 Microporous article having a stabilized specific binding reagent, a method for its use and a diagnostic test kit EASTMAN KODAK CO (US) 1994-07-27 EP disclosed
EP-0525916-A1 Diluent composition Johnson & Johnson Clinical Diagnostics, Inc. (US) 1993-02-03 EP disclosed
US-5155021-A METHOD AND KIT FOR DETERMINATION OF HERPES SIMPLEX VIRAL ANTIGEN BY DIRECT BINDING TO POLYMERIC PARTICLES EASTMAN KODAK COMPANY (US) 1992-10-13 US disclosed
US-5086143-A COPOLYMERS CONTAINING POLYOXYALKYLENE SIDE CHAINS EASTMAN KODAK COMPANY (US) 1992-02-04 US disclosed
EP-0468584-A2 Copolymers containing polyoxyalkylene side chains Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-29 EP disclosed
EP-0347137-A2 Microporous article having a stabilized specific binding reagent, a method for its use and a diagnostic test kit EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-12-20 EP disclosed
WO-1989009939-A1 COMPOSITIONS, DIAGNOSTIC KIT AND METHOD FOR RAPID DETECTION OF ANTIBODIES EASTMAN KODAK COMPANY (US) 1989-10-19 WO disclosed
EP-0337785-A1 Diagnostic kit and method for rapid detection of antibodies Johnson & Johnson Clinical Diagnostics, Inc. (US) 1989-10-18 EP disclosed