Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | PGR | P06401 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944917 | 0.82 | SHBG (0.36) | ESR1CHRM2SLC6A2SLC6A4CYP2C19 | |
| SCHEMBL9543840 | 0.80 | CYP19A1 (0.55) | ESR1SLC6A4CYP2C19ALDH1A1LMNA | |
| SCHEMBL3775778 | 0.77 | ESR1 (0.55) | ESR1CHRM2SLC6A2SLC6A4CYP2C19 | |
| SCHEMBL2508395 | 0.77 | ESR1 (0.57) | ESR1CHRM2SLC6A2SLC6A4CYP2C19 | |
| SCHEMBL11874257 | 0.77 | ESR1 (0.57) | ESR1CHRM2SLC6A2SLC6A4CYP2C19 | |
| SCHEMBL11866439 | 0.75 | SLC6A4 (0.61) | ESR1CHRM2SLC6A2SLC6A4CYP2C19 | |
| SCHEMBL30361235 | 0.74 | ESR1 (0.57) | ESR1CHRM2SLC6A2SLC6A4CYP2C19 | |
| SCHEMBL30697545 | 0.72 | SHBG (0.34) | ESR1CHRM2SLC6A2SLC6A4CYP2C19 | |
| SCHEMBL30944712 | 0.72 | CYP19A1 (0.32) | ALDH1A1SHBGSERPINA6SLC22A1THRB | |
| SCHEMBL9199648 | 0.71 | ESR1 (0.64) | ESR1CHRM2SLC6A2SLC6A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003002058-A9 | BONE ANABOLIC COMPOUNDS AND METHODS OF USE | ANABONIX INC (US) | 2004-07-08 | — | — | WO | claimed |
| EP-1404344-A2 | BONE ANABOLIC COMPOUNDS AND METHODS OF USE | Anabonix, Inc. (US) | 2004-04-07 | — | — | EP | claimed |
| US-20030119800-A1 | Bone anabolic compounds and methods of use | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2003-06-26 | — | — | US | claimed |
| WO-2003002058-A2 | BONE ANABOLIC COMPOUNDS AND METHODS OF USE | ANABONIX, INC. (US) | 2003-01-09 | — | — | WO | claimed |
| WO-1993025569-A1 | OESTRADIOL PRODRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-12-23 | — | — | WO | claimed |
| CN-113243458-B | Novel prebiotics and application thereof in livestock and poultry breeding | 云南省畜牧兽医科学院 | 2022-02-11 | — | — | CN | disclosed |
| CN-113243458-A | Novel prebiotics and application thereof in livestock and poultry breeding | 云南省畜牧兽医科学院 | 2021-08-13 | — | — | CN | disclosed |
| US-20080075772-A1 | PHARMACEUTICAL COMPOSITIONS HAVING NOVEL SCORING PATTERNS AND METHODS OF USING THOSE COMPOSITIONS | ACCU-BREAK TECHNOLOGIES, INC. | 2008-03-27 | — | — | US | disclosed |
| WO-2003002058-A9 | BONE ANABOLIC COMPOUNDS AND METHODS OF USE | ANABONIX INC (US) | 2004-07-08 | — | — | WO | disclosed |
| EP-1404344-A2 | BONE ANABOLIC COMPOUNDS AND METHODS OF USE | Anabonix, Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| US-20030119800-A1 | Bone anabolic compounds and methods of use | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2003-06-26 | — | — | US | disclosed |
| WO-2003002058-A2 | BONE ANABOLIC COMPOUNDS AND METHODS OF USE | ANABONIX, INC. (US) | 2003-01-09 | — | — | WO | disclosed |
| WO-1993025569-A1 | OESTRADIOL PRODRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119800-A1 | Bone anabolic compounds and methods of use | SHBG, BMP2, BMP4 | ESR1 220/4885CHRM2 2294/4885SLC6A2 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.