Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.32 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652905 | 0.78 | CYP19A1 (0.53) | CYP19A1SERPINA6SLC22A1ALDH1A1SHBG | |
| SCHEMBL9543840 | 0.78 | CYP19A1 (0.55) | CYP19A1SERPINA6SLC22A1ALDH1A1SHBG | |
| SCHEMBL4940493 | 0.72 | ESR1 (0.51) | CYP19A1SERPINA6SLC22A1ALDH1A1SHBG | |
| SCHEMBL11017258 | 0.71 | CYP19A1 (0.60) | CYP19A1SERPINA6ALDH1A1SHBG | |
| SCHEMBL6437488 | 0.71 | SHBG (0.62) | CYP19A1SERPINA6SLC22A1ALDH1A1SHBG | |
| SCHEMBL10705601 | 0.68 | CYP19A1 (0.56) | CYP19A1SERPINA6SLC22A1ALDH1A1SHBG | |
| SCHEMBL19073470 | 0.68 | LMNA (0.38) | CYP19A1ALDH1A1SHBG | |
| SCHEMBL24476668 | 0.67 | CYP3A4 (0.66) | ALDH1A1SHBGTHRB | |
| SCHEMBL13415930 | 0.66 | CYP17A1 (0.52) | CYP19A1SERPINA6ALDH1A1 | |
| SCHEMBL3127415 | 0.66 | SHBG (0.62) | CYP19A1SERPINA6SLC22A1ALDH1A1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4637929-A1 | COADMINISTRATION OF ESTROGEN WITH ESTROGEN RECEPTOR MODULATOR OR DEGRADER OR ER TARGETED PROTAC FOR THE TREATMENT OF ESTROGEN RESPONSIVE CANCERS | Duke University (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024138077-A1 | COADMINISTRATION OF ESTROGEN WITH ESTROGEN RECEPTOR MODULATOR OR DEGRADER OR ER TARGETED PROTAC FOR THE TREATMENT OF ESTROGEN RESPONSIVE CANCERS | DUKE UNIVERSITY (US) | 2024-06-27 | — | — | WO | disclosed |