Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100037 | 0.82 | MAP3K14 (0.40) | MAP3K14CRBNDDB1MEN1APEX1 | |
| SCHEMBL2896147 | 0.77 | MEN1 (0.47) | MAP3K14CRBNDDB1MEN1APEX1 | |
| SCHEMBL21658858 | 0.76 | MAP3K14 (0.46) | MAP3K14CRBNDDB1MEN1APEX1 | |
| SCHEMBL2711511 | 0.74 | MAP3K14 (0.44) | MAP3K14CRBNDDB1MEN1APEX1 | |
| SCHEMBL514603 | 0.74 | ALDH1A1 (0.52) | MAP3K14CRBNDDB1MEN1APEX1 | |
| SCHEMBL7158837 | 0.73 | CRBN (0.34) | MAP3K14CRBNDDB1ALDH1A1 | |
| SCHEMBL6511682 | 0.72 | MAP3K14 (0.43) | MAP3K14CRBNDDB1MEN1APEX1 | |
| SCHEMBL11022447 | 0.72 | TSHR (0.39) | MAP3K14CRBNDDB1KMT2AALDH1A1 | |
| Cyclopropane SCHEMBL15636563 | 0.71 | ALDH1A1 (0.49) | MAP3K14CRBNDDB1MEN1APEX1 | |
| SCHEMBL29889995 | 0.69 | RGS12 (0.34) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156066-A1 | ECO-FRIENDLY MATERIALS AND METHODS FOR RENEWABLE AND SUSTAINABLE APPLICATIONS IN MATERIAL CHEMISTRY | NDSU RESEARCH FOUNDATION (US) | 2017-09-14 | — | — | WO | disclosed |
| US-7375061-B2 | Antioxidant hydrazides and derivatives thereof having multifunctional activity | CROMPTON CORPORATION (US) | 2008-05-20 | — | — | US | disclosed |
| CN-1271182-C | Tri-glycerinate vegetable oil-succinhydrazide additives for lubricants | UNIROYAL CHEM CO INC (US) | 2006-08-23 | — | — | CN | disclosed |
| WO-2006028567-A1 | ANTIOXIDANT HYDRAZIDES AND DERIVATIVES THEREOF HAVING MULTIFUNCTIONAL ACTIVITY | CHEMTURA CORPORATION (US) | 2006-03-16 | — | — | WO | disclosed |
| US-20060052260-A1 | Antioxidant hydrazides and derivatives thereof having multifunctional activity | CROMPTON CORPORATION | 2006-03-09 | — | — | US | disclosed |
| EP-1461403-B1 | TRI-GLYCERINATE VEGETABLE OIL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | UNIROYAL CHEM CO INC (US) | 2006-01-25 | — | — | EP | disclosed |
| CN-1606610-A | Tri-glycerinate vegetable oil-succinhydrazide additives for lubricants | UNIROYAL CHEM CO INC (US) | 2005-04-13 | — | — | CN | disclosed |
| EP-1461403-A1 | TRI-GLYCERINATE VEGETABLE OIL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | Uniroyal Chemical Company, Inc. (US) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003048279-A1 | TRI-GLYCERINATE VEGETABLE OIL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2003-06-12 | — | — | WO | disclosed |
| US-6559106-B1 | Ashless and non- phosphorus, non-sulfur-containing anti-wear, anti-fatigue, extreme pressure, and anti-corrosion additives derived from tri- glycerinate vegetable oil-succinhydrazides | UNIROYAL CHEMICAL COMPANY, INC. | 2003-05-06 | — | — | US | disclosed |