Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 10/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28450776 | 0.71 | CHRNB2 (0.36) | OPRL1OPRM1OPRK1SLC6A2 | |
| SCHEMBL123293 | 0.69 | MAOB (0.33) | OPRL1OPRM1OPRK1SLC6A2 | |
| SCHEMBL28114366 | 0.67 | HDAC9 (0.39) | — | |
| SCHEMBL27897540 | 0.66 | HDAC1 (0.41) | — | |
| SCHEMBL10786327 | 0.62 | NPC1 (0.43) | OPRL1OPRM1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL21676 | 0.60 | CA12 (0.45) | SIGMAR1 | |
| Ammonia Solution, Strong SCHEMBL3205919 | 0.58 | CA12 (0.44) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL27301016 | 0.58 | CA12 (0.44) | SIGMAR1 | |
| SCHEMBL4089733 | 0.58 | HDAC4 (0.36) | OPRL1OPRM1OPRK1 | |
| SCHEMBL31442138 | 0.58 | HDAC9 (0.35) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004470-A1 | Synthesis of Atomoxetine Hydrochloride | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-01-03 | — | — | US | disclosed |
| EP-1794112-A1 | SYNTHESIS OF ATOMOXETINE HYDROCHLORIDE | Dr. Reddy's Laboratories Ltd. (IN) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006037055-A1 | SYNTHESIS OF ATOMOXETINE HYDROCHLORIDE | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004470-A1 | Synthesis of Atomoxetine Hydrochloride | SLC6A2, SLC6A4, SLC6A3 | OPRL1 9/4885OPRM1 12/4885OPRK1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.