Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | SI | P14410 | 1/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.55 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943398 | 0.88 | SLC9A1 (0.58) | SLC9A1S1PR4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4936895 | 0.85 | ALDH1A1 (0.50) | SLC9A1S1PR4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4936806 | 0.84 | SLC9A1 (0.61) | SLC9A1S1PR4ALDH1A1MAPTKDM4E | |
| SCHEMBL4937176 | 0.82 | SLC9A1 (0.59) | SLC9A1S1PR4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27585207 | 0.82 | SLC9A1 (0.72) | SLC9A1S1PR4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4941158 | 0.80 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2MAPTKDM4ERAB9A | |
| SCHEMBL4944299 | 0.80 | S1PR4 (0.51) | SLC9A1S1PR4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4946319 | 0.79 | SLC9A1 (0.61) | SLC9A1S1PR4ALDH1A1MAPTKDM4E | |
| SCHEMBL4944695 | 0.79 | CYP1A2 (0.62) | SLC9A1ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL3719608 | 0.78 | SLC9A1 (0.59) | SLC9A1S1PR4ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351843-B2 | Furancarbonylguanidine derivatives, their preparation and pharmaceutical compositions containing them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-04-01 | — | — | US | disclosed |
| US-20070299131-A1 | Furancarbonylguanidine Derivatives, Their Preparation and Pharmaceutical Compositions Containing Them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299131-A1 | Furancarbonylguanidine Derivatives, Their Preparation and Pharmaceutical Compositions Containing Them | SLC9A1, NHERF1, SLC5A1 | SLC9A1 1/4885S1PR4 2223/4885ALDH1A1 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.