Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31311097 | 0.71 | PARL (0.43) | MEN1LMNAHPGDKMT2A | |
| SCHEMBL3083570 | 0.59 | GAA (0.31) | — | |
| SCHEMBL1829012 | 0.58 | HTT (0.49) | MEN1LMNAKMT2A | |
| SCHEMBL4792080 | 0.58 | MAPT (0.41) | MEN1LMNAKMT2A | |
| SCHEMBL27922051 | 0.57 | KMT2A (0.47) | MEN1LMNAHPGDKMT2A | |
| SCHEMBL9390020 | 0.57 | MAPT (0.52) | — | |
| SCHEMBL28014485 | 0.56 | BRD4 (0.35) | MEN1LMNAKMT2A | |
| SCHEMBL25290828 | 0.55 | GAA (0.50) | — | |
| SCHEMBL7328852 | 0.55 | MAPT (0.50) | LMNA | |
| SCHEMBL31406264 | 0.55 | GAA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306045-A1 | 1-Benzazepine-3-Sulfonylamino-2-Pyrroridones as Factor Xa Inhibitors | CAMUS LAURE | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306045-A1 | 1-Benzazepine-3-Sulfonylamino-2-Pyrroridones as Factor Xa Inhibitors | TFPI, TPSAB1, TFPI2 | MEN1 893/4885LMNA 811/4885HPGD 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.