Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2084284 | 0.73 | ATM (0.51) | LMNAMEN1KMT2AHTTATM | |
| SCHEMBL5635263 | 0.72 | MAPT (0.51) | LMNAMEN1KMT2AHTTSMN1; SMN2 | |
| Methylpyrrolidone SCHEMBL3476278 | 0.72 | BRD4 (0.50) | PARLLMNAMEN1KMT2AHPGD | |
| SCHEMBL1829012 | 0.72 | HTT (0.49) | LMNAMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL7115197 | 0.72 | LMNA (0.53) | LMNAMEN1KMT2AHTTATM | |
| SCHEMBL3799154 | 0.72 | LMNA (0.53) | LMNAMEN1KMT2AHTTATM | |
| SCHEMBL4944309 | 0.71 | MEN1 (0.31) | LMNAMEN1KMT2AHPGD | |
| SCHEMBL7380549 | 0.70 | PKM (0.62) | PARLLMNAMEN1KMT2ARCE1 | |
| Hydrochloric Acid SCHEMBL11538425 | 0.70 | ATM (0.53) | LMNAMEN1KMT2AHPGDHTT | |
| SCHEMBL29174211 | 0.70 | HTT (0.56) | MEN1KMT2AHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699189-B | Modulators of beta-3 adrenergic receptors useful for treating or preventing heart failure and disorders associated therewith | 艾尼纳制药公司 | 2025-02-18 | — | — | CN | disclosed |