Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688876 | 0.93 | HSD17B10 (0.60) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL29563927 | 0.93 | HSD17B10 (0.60) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL2834703 | 0.84 | HSD17B10 (0.75) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL7598992 | 0.83 | HSD17B10 (0.46) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL3299164 | 0.83 | KMT2A (0.45) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL31590375 | 0.82 | HSD17B10 (0.72) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL31590816 | 0.82 | HSD17B10 (0.72) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4607898 | 0.82 | HSD17B10 (0.72) | HSD17B10NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL4944634 | 0.82 | THRB (0.52) | HSD17B10ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL3293879 | 0.80 | ALDH1A1 (0.44) | HSD17B10ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |