SCHEMBL4944673

SCHEMBL4944673

CCCCC1(C(=O)CP(=O)(OC)OC)CCC1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
CETP P11597 4/20 0.35
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10802478 0.97 CYP4F2 (0.40) CYP4F2CYP4A11CETPFAAH
SCHEMBL11717601 0.95 CYP4F2 (0.39) CYP4F2CYP4A11CETPFAAH
SCHEMBL11626602 0.94 CYP4F2 (0.41) CYP4F2CYP4A11CETPFAAH
SCHEMBL11623451 0.90 CYP4F2 (0.32) CYP4F2CYP4A11CETP
SCHEMBL960407 0.85 CYP4F2 (0.38) CYP4F2CYP4A11
SCHEMBL11722094 0.82 LPAR3 (0.38) CYP4F2CYP4A11CETP
SCHEMBL10799734 0.79 CETP (0.40) CYP4F2CYP4A11CETP
SCHEMBL7699112 0.78 ALDH1A1 (0.44)
SCHEMBL9686956 0.78
SCHEMBL11624195 0.78 LPAR3 (0.41) CYP4F2CYP4A11CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7419999-B2 Gamma lactams as prostaglandin agonists and use thereof APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) 2008-09-02 US disclosed
US-20050288357-A1 Gamma lactams as prostaglandin agonists and use thereof APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2005-12-29 US disclosed
US-4117119-A 15-CYCLOBUTYL-PROSTAGLANDINS ONO PHARMACEUTICAL COMPANY (JP) 1978-09-26 US disclosed
US-4045468-A GASTRIC ULCERS ONO PHARMACEUTICAL COMPANY (JA) 1977-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288357-A1 Gamma lactams as prostaglandin agonists and use thereof PGF, HPGDS, PTGIS CYP4F2 1220/4885CYP4A11 151/4885CETP 2474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.