Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846680 | 0.86 | KMT2A (0.55) | KMT2ACASP6ALDH1A1KDM4EMAPT | |
| SCHEMBL14678 | 0.84 | CYP1A2 (0.57) | CYP1A2ALDH1A1KDM4EMAPTHTR3A | |
| SCHEMBL29418017 | 0.84 | CYP1A2 (0.57) | CYP1A2ALDH1A1KDM4EMAPTHTR3A | |
| Hydrochloric Acid SCHEMBL8324913 | 0.82 | CYP1A2 (0.55) | CYP1A2ALDH1A1KDM4EMAPTHTR3A | |
| Hydrochloric Acid SCHEMBL7362443 | 0.82 | CYP1A2 (0.55) | CYP1A2ALDH1A1KDM4EMAPTHTR3A | |
| Hydrochloric Acid SCHEMBL29862578 | 0.82 | CYP1A2 (0.55) | CYP1A2ALDH1A1KDM4EMAPTHTR3A | |
| Ethylene SCHEMBL28325267 | 0.81 | CYP1A2 (0.53) | CYP1A2ALDH1A1KDM4EMAPTHTR3A | |
| SCHEMBL2853700 | 0.76 | ALDH1A1 (0.56) | KMT2ACYP1A2ALDH1A1KDM4EMAPT | |
| Quinoline SCHEMBL28292612 | 0.76 | ALDH1A1 (0.67) | KMT2ACYP1A2CASP6ALDH1A1KDM4E | |
| Acetic Acid SCHEMBL7836636 | 0.73 | MGAM (0.57) | KMT2ACYP1A2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300236-A1 | QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR | CODD ELLEN | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300236-A1 | QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR | TRPV1, OPRL1, TRPV2 | KMT2A 2415/4885CYP1A2 905/4885CASP6 3563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.