Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140554 | 0.91 | VCAM1 (0.60) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL9373575 | 0.85 | VCAM1 (0.54) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7023145 | 0.84 | VCAM1 (0.57) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL4668707 | 0.81 | XDH (0.52) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL26926452 | 0.79 | VCAM1 (0.48) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL10928662 | 0.78 | SMN1; SMN2 (0.54) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL4667166 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MEN1MAPT | |
| SCHEMBL4667754 | 0.77 | STS (0.67) | VCAM1ALDH1A1LMNACYP19A1CA12 | |
| SCHEMBL31227792 | 0.77 | VCAM1 (0.64) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL1342722 | 0.77 | VCAM1 (0.64) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4521345-A | Aromatic coupling process | ETHYL CORPORATION (US) | 1985-06-04 | — | — | US | claimed |
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |
| US-4521345-A | Aromatic coupling process | ETHYL CORPORATION (US) | 1985-06-04 | — | — | US | disclosed |
| US-4521345-A | Aromatic coupling process | ETHYL CORPORATION (US) | 1985-06-04 | — | — | US | disclosed |