Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800518 | 0.86 | ACHE (0.55) | SLC6A7ACHEPKMKDM4EOGA | |
| SCHEMBL15285931 | 0.81 | SLC6A7 (0.66) | SLC6A7ACHEALDH1A1HSD17B10KDM4E | |
| SCHEMBL2228019 | 0.81 | PANK3 (0.58) | SLC6A7GAAACHEALDH1A1TSHR | |
| SCHEMBL17438471 | 0.81 | ALDH1A1 (0.40) | KDM1AALDH1A1TSHRHSD17B10 | |
| SCHEMBL19015403 | 0.79 | ACHE (0.61) | ACHE | |
| SCHEMBL4498884 | 0.78 | ACHE (0.52) | SLC6A7ACHETSHRKDM4E | |
| SCHEMBL2856220 | 0.78 | GAA (0.61) | SLC6A7GAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL4947574 | 0.78 | KDM1A (0.48) | GAAACHEKDM1AALDH1A1HSD17B10 | |
| SCHEMBL10187275 | 0.78 | KDM1A (0.48) | ACHEKDM1APKMOGA | |
| SCHEMBL5232026 | 0.78 | SLC6A7 (0.68) | SLC6A7ALDH1A1HSD17B10PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |