Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | CLPP | Q16740 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BRS3 | P32247 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949034 | 0.85 | MEN1 (0.53) | ACHEAKR1B1SLC6A5ADORA1KMT2A | |
| SCHEMBL17877207 | 0.79 | BRD4 (0.56) | ACHESLC6A5GABRA1GABRA2 | |
| SCHEMBL25967024 | 0.77 | ALDH1A1 (0.45) | HCAR2CLPPKMT2A | |
| SCHEMBL3391569 | 0.75 | ACHE (0.49) | ACHESLC6A5GABRA1GABRA2KMT2A | |
| SCHEMBL5953472 | 0.75 | HCAR2 (0.56) | HCAR2KMT2A | |
| SCHEMBL2952288 | 0.75 | SLC6A5 (0.56) | ACHESLC6A5ADORA1KMT2ABRS3 | |
| SCHEMBL11947240 | 0.74 | KMT2A (0.49) | ADORA1CLPPKMT2A | |
| SCHEMBL25344664 | 0.74 | KDM4E (0.46) | CLPP | |
| SCHEMBL17576681 | 0.73 | PEX14 (0.57) | ACHEKMT2A | |
| SCHEMBL4944611 | 0.73 | KDM4E (0.47) | ADORA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885725-B1 | TRICYCLIC AZOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-09-24 | — | — | EP | disclosed |