Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15367055 | 0.96 | ESR1 (0.52) | ESR1ESR2HSD17B1HSD17B2CYP11B1 | |
| SCHEMBL4314881 | 0.96 | ESR1 (0.52) | ESR1ESR2HSD17B1HSD17B2CYP11B1 | |
| SCHEMBL15366592 | 0.96 | ESR1 (0.55) | ESR1ESR2HSD17B1HSD17B2CYP11B1 | |
| SCHEMBL24174187 | 0.92 | HSD17B1 (0.52) | ESR1ESR2HSD17B1HSD17B2CYP11B1 | |
| SCHEMBL15366644 | 0.91 | ESR1 (0.50) | ESR1ESR2HSD17B1HSD17B2CYP11B1 | |
| SCHEMBL22708077 | 0.90 | HSD17B1 (0.53) | ESR1ESR2HSD17B1HSD17B2CYP11B1 | |
| SCHEMBL27872147 | 0.90 | ESR1 (0.53) | ESR1ESR2HSD17B1HSD17B2CYP11B1 | |
| SCHEMBL2964301 | 0.90 | ESR1 (0.47) | ESR1ESR2HSD17B1HSD17B2CYP11B1 | |
| SCHEMBL24618933 | 0.90 | HSD17B1 (0.53) | ESR1ESR2HSD17B1HSD17B2CYP11B1 | |
| SCHEMBL15366606 | 0.90 | ESR1 (0.53) | ESR1ESR2HSD17B1HSD17B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9099654-B2 | Benzofluorene compound, emission materials and organic electroluminescent device | JNC CORPORATION (JP) | 2015-08-04 | — | — | US | disclosed |
| US-20130134405-A1 | BENZOFLUORENE COMPOUND, EMISSION MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE | JNC CORPORATION (JP) | 2013-05-30 | — | — | US | disclosed |
| US-20080160347-A1 | Benzofluorene compound, emission materials and organic electroluminescent device | JNC CORPORATION (JP) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080160347-A1 | Benzofluorene compound, emission materials and organic electroluminescent device | LEF1, TRPA1, BRD8 | ESR1 58/4885ESR2 193/4885HSD17B1 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.